By Efraim Racker
Part I describes the mechanism of lymphocyte activation, the constitution and serve as of the plasma membrane, and the macromolecular synthesis in the course of lymphocyte activation. This half additionally offers with the interplay of lymphocytes with mitogenic lectins, the comparability of the mitogenic and nonmitogenic lectin binding, and the function of macrophages within the reaction of lymphocytes to lectins. half II explores the thymic elements and the improvement of attribute markers, antigens, and receptors. This half quite emphasizes lymphocyte differentiation. elements III and IV learn the genetic keep watch over and intercellular interactions all for leukocyte functionality and the parameters of the immune reaction lower than in vitro stipulations. Chapters on cytotoxicity, the mechanisms of phagocytic killing, autoimmunity, and the responses of leukocytes to tumor cells are integrated in those components. half V discusses the interactions of viruses and leukocytes and offers information at the actual mapping and research of sarcoma and leukemia viruses, whereas half VI considers the appliance of leukocyte tradition to difficulties of scientific medication. half VII includes the learn of radiation results, with an emphasis at the program of overall lymphoid irradiation to the induction of transplantation tolerance. This half additionally appears into the position of the DNA fix strategy.
Cell biologists, immunologists, and biomedical scientists and researchers will vastly reap the benefits of this book.
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